Das kommt bei mir, bei 3.3Volt:

Programming Target...
ICDWarn0052: MPLAB ICD 2 cannot validate a target device. Please make sure that the target device is connected and properly powered. Select "OK" to continue, or "CANCEL" to abort the operation
ICD0200: Operation Aborted (Warning 51).
ICD0275: Programming failed.
MPLAB ICD 2 Ready


Gerhard